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Last updateTue, 30 Aug 2016 11am

Pharmacogenomic Markers

Pharmacogenomic Markers

This module of FINDbase database documents the frequencies of pharmacogenetically relevant single nucleotide polymorphisms (SNPs) in various populations worldwide [in preparation]. Database records include the population, the ethnic group and/or the geographic region, the gene name and its variation parameters, the rare allele frequencies, accompanied by links to the respective Online Mendelian Inheritance in Man (OMIM) and the PharmGKB entries. All entries are recorded against their unique PubMed and ResearcherIDs.

The current data collection of this module includes curated allelic frequency data for 144 pharmacogenomic markers across 14 genes, representing approximately 87,000 individuals from 150 populations worldwide.

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As molecular genetic testing and electronic healthcare records become increasingly common features of modern medical practice, there is a need to integrate information in genetic databases to establish a detailed understanding of how genome sequence differences impact on human health.

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