Thursday, 05 23rd 2013

Last updateMon, 26 Mar 2012 12pm

History

June 2010: FINDbase completed its upgrade, using PivotViewer and Silverlight technology. In particular, the new FINDbase data querying and visualization environment enables the user to visualize and sort, organize and categorize data dynamically and discover trends across all items, using different views, while is also allows compound queries to be formulated.
May 2008: Human Genomics and Proteomics was officially launched and became the first scientific peer-reviewed journal linked to a database (FINDbase). This innovative publication modality marked a new era in scientific publication and was well perceived internationally.
September 2007: Initial agreement with SAGE and HINDAWI to launch the first database-journal, based on FINDbase. The idea was that Genomic variation allele frequency data are submitted to the journal as a Mutation and Biomarker Dataset with links to the full dataset in FINDbase. Once accepted, the data become available in FINDbase and the respective article indexed in PubMed to provide credit to authors for their submission.
March 2007: Inclusion of pharmacogenomic markers allele frequencies in FINDbase was initiated. Prior knowledge of pharmacogenomic markers allele frequencies are important in order to personalize drug treatment in various populations and as such, FINDbase has satisfied the need of a centralized database documenting pharmacogenomic marker allele frequencies in various populations worldwide.
November 2006: FINDbase was first reported in the 2007 annual Nucleic Acids Research database issue, indicating the high quality of this online resource in the niche environment of national/ethnic genetic databases.
April 2006: FINDbase received its first seed funding from the EuroGenTest European Network of Excellence. This funding, including already available sponsorship from Asclepion Genetics, a Swiss diagnostic company, allowed the database to develop further and enrich its records to become a comprehensive resource of causative variation allele frequencies.
March 2006: The first version of FINDbase was launched in the Golden Helix Server including causative mutation allele frequencies from over 80 populations and ethnic groups worldwide. At that time, FINDbase was the richest National genetic database in terms of records.
March 2005: The FINDbase concept was first proposed by the ErasmusMC group of George Patrinos. The aim was to fill in the existing gap, at that time, of documenting genomic variation allele frequencies of clinical significance in an effort to provide a better aid for personalized medicine.

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As molecular genetic testing and electronic healthcare records become increasingly common features of modern medical practice, there is a need to integrate information in genetic databases to establish a detailed understanding of how genome sequence differences impact on human health.

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